Abstract

This study aimed to analyze the antidiabetic activity using amylase inhibition of the dichloromethane extract fraction. The semipolar dichloromethane fraction with inhibitory power of 89.77 ± 0.01% and I050 value of 3.25 ± 0.20 μg/mL was followed by ethyl acetate fraction with inhibitory activity of 87.42. ± 0.04% and I050 value of 3.33 ± 0.15 μg/mL were more active in inhibiting the amylase enzyme than the methanol and n-hexane fractions. The inhibition results of the four active fractions were close to the standard acarbose. It was concluded that G. forbesii could be a potential antidiabetic agent in the future.

Original languageEnglish
Title of host publication1st International Seminar on Chemistry and Chemistry Education, ISCCE 2021
EditorsDominggus Malle, Nikmans Hattu, Healthy Kainama, Colincie Natalia Labetubum, I. Wayan Sutapa
PublisherAmerican Institute of Physics Inc.
ISBN (Electronic)9780735443044
DOIs
Publication statusPublished - 11 Jan 2023
Event1st International Seminar on Chemistry and Chemistry Education, ISCCE 2021 - Ambon, Virtual, Indonesia
Duration: 23 Sept 202124 Sept 2021

Publication series

NameAIP Conference Proceedings
Volume2642
ISSN (Print)0094-243X
ISSN (Electronic)1551-7616

Conference

Conference1st International Seminar on Chemistry and Chemistry Education, ISCCE 2021
Country/TerritoryIndonesia
CityAmbon, Virtual
Period23/09/2124/09/21

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