12 Citations (Scopus)

Abstract

One of the most frequent and widespread infectious diseases especially in developing countries is tuberculosis (TB). The number of TB drug resistant tend to increase, and there has been no new TB drug introduce since the 1960s. Six 2-Thiophenecarboxylic acid hydrazide derivatives were synthesized in 90-97% yields, and 2-thiophenecarbonylhydrazone-5, 7-dibromoisatin showed the highest activity in inhibiting M. tuberculosis H37Rv.

Original languageEnglish
Article number012039
JournalIOP Conference Series: Materials Science and Engineering
Volume349
Issue number1
DOIs
Publication statusPublished - 2 May 2018
Event12th Joint Conference on Chemistry, JCC 2017 - Semarang, Indonesia
Duration: 19 Sept 201720 Sept 2017

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