TY - JOUR
T1 - 2-Thiophenecarboxylic acid hydrazide Derivatives
T2 - 12th Joint Conference on Chemistry, JCC 2017
AU - Fahmi, M. R.G.
AU - Khumaidah, L.
AU - Ilmiah, T. K.
AU - Fadlan, A.
AU - Santoso, M.
N1 - Publisher Copyright:
© 2018 Institute of Physics Publishing. All rights reserved.
PY - 2018/5/2
Y1 - 2018/5/2
N2 - One of the most frequent and widespread infectious diseases especially in developing countries is tuberculosis (TB). The number of TB drug resistant tend to increase, and there has been no new TB drug introduce since the 1960s. Six 2-Thiophenecarboxylic acid hydrazide derivatives were synthesized in 90-97% yields, and 2-thiophenecarbonylhydrazone-5, 7-dibromoisatin showed the highest activity in inhibiting M. tuberculosis H37Rv.
AB - One of the most frequent and widespread infectious diseases especially in developing countries is tuberculosis (TB). The number of TB drug resistant tend to increase, and there has been no new TB drug introduce since the 1960s. Six 2-Thiophenecarboxylic acid hydrazide derivatives were synthesized in 90-97% yields, and 2-thiophenecarbonylhydrazone-5, 7-dibromoisatin showed the highest activity in inhibiting M. tuberculosis H37Rv.
UR - http://www.scopus.com/inward/record.url?scp=85047721033&partnerID=8YFLogxK
U2 - 10.1088/1757-899X/349/1/012039
DO - 10.1088/1757-899X/349/1/012039
M3 - Conference article
AN - SCOPUS:85047721033
SN - 1757-8981
VL - 349
JO - IOP Conference Series: Materials Science and Engineering
JF - IOP Conference Series: Materials Science and Engineering
IS - 1
M1 - 012039
Y2 - 19 September 2017 through 20 September 2017
ER -