Medical wastes bring probable hazards and public risks if not handled correctly, especially during the covid-19 pandemic. Waste management costs are rising due to continues devastation of covid-19 virus. Increased care and handling processes have been implemented to avoid further spreading the infection while ensuring the proper disposal. Given this, medical waste related to covid-19, including other wastes generated by medical facilities, requires delicate integration into the waste management process thru a reverse logistics network for cost-efficient collection, processing, and transport style. Using AMPL software as solving tool, this paper was designed to utilize a mixed-integer linear programming model of a reverse logistics network to improve medical waste management by identifying the total minimum cost of the waste disposal cycle from Waste generating facilities, treatment facilities, and to the disposal factory.