Nowadays web based applications are widely used in education field. Web based applications are used primarily to support the business processes of educational institutions such as Academic Information System (AIS). However, not all of AIS is well managed. Therefore, we need an instrument that can measure the quality and ensure the quality of AIS. This paper introduced a framework for measuring the quality of web based AIS using visitors, developers and institutions perspectives approach. AIS quality instrument built from the combination of ISO/IEC 9126, ISO/IEC 25010:2011, WBA Quality Model, and COBIT 4.1. This framework is expected to produce a measurement of academic quality web-based information systems more accurately and provide detailed recommendations in order to produce a better system, especially to support the business processes of AIS.