TY - GEN
T1 - Analysis of protein profiles in diabetic rat blood plasma that induced by alloxan
AU - Hidayati, Dewi
AU - Abdulgani, Nurlita
AU - Setiyawan, Hengki
AU - Trisnawati, Indah
AU - Ashuri, Nova Maulidina
AU - Sa'Adah, Noor Nailis
N1 - Publisher Copyright:
© 2017 Author(s).
PY - 2017/6/26
Y1 - 2017/6/26
N2 - Proteomics is the study to identify the proteins involved in physiological metabolic pathway. The protein profiles of blood plasma from alloxan-induced diabetic rats has investigated using Sodium Dodecyl Sulphate Polyacrylamide Gel Electrophoresis (SDS-PAGE). Data were analyzed descriptively based on variations of the type and intensity of the protein. There were identified the similarity of protein variant between diabetic and control rats included ankyrin (200kDa), IgG (150kDa), nephrin (136 kDa), IDE (112 kDA), albumin (66 kDa), prealbumin (55 kDA), CICP (43 kDa), ApoA-V (39 kDa), GAPDH (35 kDa), C-RP (27,1 kDa), leptin (16 kDa) and apelin (13 kDa). However, the apelin profile at diabetic rats shows the higher intensity than control.
AB - Proteomics is the study to identify the proteins involved in physiological metabolic pathway. The protein profiles of blood plasma from alloxan-induced diabetic rats has investigated using Sodium Dodecyl Sulphate Polyacrylamide Gel Electrophoresis (SDS-PAGE). Data were analyzed descriptively based on variations of the type and intensity of the protein. There were identified the similarity of protein variant between diabetic and control rats included ankyrin (200kDa), IgG (150kDa), nephrin (136 kDa), IDE (112 kDA), albumin (66 kDa), prealbumin (55 kDA), CICP (43 kDa), ApoA-V (39 kDa), GAPDH (35 kDa), C-RP (27,1 kDa), leptin (16 kDa) and apelin (13 kDa). However, the apelin profile at diabetic rats shows the higher intensity than control.
KW - alloxan
KW - blood plasma
KW - diabetes
KW - proteomics
UR - http://www.scopus.com/inward/record.url?scp=85023182969&partnerID=8YFLogxK
U2 - 10.1063/1.4985407
DO - 10.1063/1.4985407
M3 - Conference contribution
AN - SCOPUS:85023182969
T3 - AIP Conference Proceedings
BT - Proceeding of International Biology Conference 2016
PB - American Institute of Physics Inc.
T2 - 3rd International Biology Conference 2016: Biodiversity and Biotechnology for Human Welfare, IBOC 2016
Y2 - 15 October 2016
ER -