Abstract

Public health is one of the main problems for the people of Indonesia. One of the causes of health problems is pathogenic bacteria from the environment that easily enter the body and multiply to produce various diseases and infections. Plants extracts are one of the most important natural resources and alternative in the treatment effort as well as improving public health. This research was conducted to determine the antibacterial activities of methanol extract from Syzygium polyanthum Wight leaves as well as its fractions against bacteria Gram-positive Staphylococcus aureus and bacteria Gram-negative Eschericia coli. Ampicillin as positive control showed antibacterial activities against S. aureus and E. coli with IC50 value of 37.82 μg/mL and 10.28 μg/mL, respectively. Methanol extract showed antibacterial activities against S. aureus and E. coli with IC50 value of 23.16 μg/mL and 35.01 μg/mL, respectively. The n-hexane fraction had the highest antibacterial activity against S. aureus and E. coli with IC50 value of 49.25 μg/mL and 27.54 μg/mL, respectively, compared with aqueous and ethyl acetate fractions. The results demonstrated of methanol extract of S. polyanthum Wight leaves and its fractions as antibacterial sources.

Original languageEnglish
Title of host publication3rd International Seminar on Chemistry
Subtitle of host publicationGreen Chemistry and Its Role for Sustainability
EditorsFredy Kurniawan, Yuly Kusumawati, Sri Fatmawati, Hendro Juwono, Adi Setyo Purnomo
PublisherAmerican Institute of Physics Inc.
ISBN (Electronic)9780735417755
DOIs
Publication statusPublished - 14 Dec 2018
Event3rd International Seminar on Chemistry: Green Chemistry and Its Role for Sustainability, ISOC 2018 - Surabaya, Indonesia
Duration: 18 Jul 201819 Jul 2018

Publication series

NameAIP Conference Proceedings
Volume2049
ISSN (Print)0094-243X
ISSN (Electronic)1551-7616

Conference

Conference3rd International Seminar on Chemistry: Green Chemistry and Its Role for Sustainability, ISOC 2018
Country/TerritoryIndonesia
CitySurabaya
Period18/07/1819/07/18

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