Central composite design based statistical modelling of curcuminoids extraction from Curcuma zedoaria using choline chloride based Natural Deep Eutectic Solvent (NADES)

O. Rachmaniah*, Istiqomah, Fakhrinanda, M. Rachimoellah

*Corresponding author for this work

Research output: Contribution to journalConference articlepeer-review

1 Citation (Scopus)

Abstract

Ionic type of Natural Deep Eutectic Solvents (NADES) consisted of choline chloride and organic acids, i.e., choline chloride-malic acid (CCMA) and choline chloride-citric acid (CCCA), known as the most suitable liquefied solvent for curcuminoids extraction from Curcuma zedoaria. A laboratory-scale extraction of curcuminoids from C. zedoaria successfully conducted; indicated that solvent per feed ratio (S/F) and extraction time are the two important variables for yielding a high extraction rate of curcuminoids. Therefore, a central composite based design is used to optimize the extraction parameters such as S/F (3/10, 5/10, 7/10), time extraction (18, 20, and 22 h), and stirring speed (200, 250, and 300 rpm) at 500 mL capacity. Stirring speed is the most influential parameter among the studied parameters. However, due to the low bulk density of C. zedoaria powder, a homogenous mixture of C. zedoaria in the extraction tank was barely achieved; hence a low yield of curcuminoids is obtained.

Original languageEnglish
Article number012011
JournalIOP Conference Series: Materials Science and Engineering
Volume823
Issue number1
DOIs
Publication statusPublished - 26 May 2020
Event2019 International Seminar on Chemical Engineering Soehadi Reksowardojo, STKSR 2019 - Kupang, Nusa Tenggara Timur, Indonesia
Duration: 7 Oct 20199 Oct 2019

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