The composite based Zinc-doped in Chitosan/Hydroxyapatite was successfully prepared by wet mixing method through the addition of 10, 15, and 20wt% of chitosan. The addition of Chitosan increased the compressive strength and the modulus elasticity. However, it decreased the density and the surface hardness of HA-Zn. Mechanical characterization revealed that these composites are suitable as a candidate of a cancellous bone substitute. Composite with 10% chitosan has compressive strength and modulus elasticity of 57.03 MPa and 0.15 GPa, respectively. Hence, it has the physical and mechanical properties that meet the standards as a cancellous bone substitute material. Also, in vitro biocompatibility test against BHK-21 cells exhibited non-toxic materials.

Original languageEnglish
Article number012080
JournalIOP Conference Series: Materials Science and Engineering
Issue number1
Publication statusPublished - 31 May 2017
Event4th International Conference on Advanced Materials Science and Technology 2016, ICAMST 2016 - Malang, Indonesia
Duration: 27 Sept 201628 Sept 2016


  • HA
  • bone
  • chitosan
  • composite
  • zinc


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