Hydroxyapatite (HAp) doping with zinc was prepared using sol gel method; different chitosan content were further added to prepare the composite, namely 10, 15 and 20% wt. The samples were characterized using FTIR, XRD, SEM-EDX, and AAS. In vitro antimicrobial activities of the composite were evaluated against gram positive and negative bacteria. FTIR results revealed that there were no important changes in the structure of composite, while 10% wt of chitosan in composite shows the highest inhibition zone against Escherichia coli after 24 h incubation. In addition, after 7 days of immersion in simulated body fluid, there were apatite formations in the surface of the composite. These might indicate that this composite could be used as a material candidate for bone substitute applications.

Original languageEnglish
Article number012063
JournalIOP Conference Series: Materials Science and Engineering
Issue number1
Publication statusPublished - 5 Aug 2017
EventInternational Conference and Exhibition on Innovation in Polymer Science and Technology 2016, IPST 2016 - Medan, North Sumatera, Indonesia
Duration: 7 Nov 201610 Nov 2016


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