Evaluation of dosimetry in case of breast cancer post mastectomy with or without bolus based on silicone rubber using intensity modulated radiation therapy

Evi Linggasari; Aditya P. Hariyanto; St Aisyah; Nurul H. Jannah; Agus Rubiyanto; Mohammad Haekal; Muhamad Fadli

doi:10.1063/5.0140137

Evaluation of dosimetry in case of breast cancer post mastectomy with or without bolus based on silicone rubber using intensity modulated radiation therapy

Evi Linggasari
, Aditya P. Hariyanto
, St Aisyah
, Nurul H. Jannah
, Agus Rubiyanto
, Mohammad Haekal
, Muhamad Fadli
, Endarko^*

^*Corresponding author for this work

Institut Teknologi Sepuluh Nopember
Mochtar Riady Comprehensive Cancer Center Siloam Hospitals

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › peer-review

Abstract

Radiation therapy treatment for post-mastectomy breast cancer usually requires a bolus to raise the surface dose to a certain level. Bolus is a compensatory material that has properties such as soft tissue or water. Therefore, this study will evaluate the potential of using bolus and without bolus in post-mastectomy breast cancer cases. This study aims to analyze the percentage surface dose (PSD) on the solid water slab phantom, dose-volume histogram (DVH), profile dose, and surface dose in Postmastectomy Radiation Therapy (PMRT) cases with and without using a bolus made of silicone rubber with a thickness of 0.5 cm. The methods used in the present study involving measuring surface dose using bolus and without bolus on a solid water slab phantom with the TRS 398 protocol, making an Intensity-modulated radiation therapy (IMRT) planning system in 5 fields with angles of 30˚, 60˚, 230˚, 260˚and 320˚. Then analyzed DVH, dose profile, and surface dose using bolus and without bolus. Finally, verification of the plans that have been made is done using EBT3 film placed at 3 points (isocenter, right, and left). The results showed that DVH with bolus and without bolus met the recommendations of the International Commission on Radiation Unit (ICRU) 62, and organ at risk (OAR) still met the tolerance limit. The percentage of surface dose reached 80.02 % and 29.75 %, respectively, for with and without bolus. The surface dose in PMRT increased up to 35%. Moreover, a bolus can increase the dose to the surface very well when the tumor cells are located on the surface compared to without a bolus.

Original language	English
Title of host publication	11th International Seminar on New Paradigm and Innovation on Natural Sciences and Its Application, ISNPINSA 2021
Subtitle of host publication	Developing Science and Technology Toward the New Normal Era
Editors	Qidir Maulana Binu Soesanto, Damar Nurwahyu Bima, Nor Basid Adiwibawa Prasetya, Heri Sugito, Alik Maulidiyah
Publisher	American Institute of Physics Inc.
ISBN (Electronic)	9780735445116
DOIs	https://doi.org/10.1063/5.0140137
Publication status	Published - 2 Jun 2023
Event	11th International Seminar on New Paradigm and Innovation on Natural Sciences and Its Application: Developing Science and Technology Toward the New Normal Era, ISNPINSA 2021 - Semarang, Virtual, Indonesia Duration: 14 Oct 2021 → 15 Oct 2021

Publication series

Name	AIP Conference Proceedings
Volume	2738
ISSN (Print)	0094-243X
ISSN (Electronic)	1551-7616

Conference

Conference	11th International Seminar on New Paradigm and Innovation on Natural Sciences and Its Application: Developing Science and Technology Toward the New Normal Era, ISNPINSA 2021
Country/Territory	Indonesia
City	Semarang, Virtual
Period	14/10/21 → 15/10/21

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 3 Good Health and Well-being

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10.1063/5.0140137

Cite this

Linggasari, E., Hariyanto, A. P., Aisyah, S., Jannah, N. H., Rubiyanto, A., Haekal, M., Fadli, M., & Endarko (2023). Evaluation of dosimetry in case of breast cancer post mastectomy with or without bolus based on silicone rubber using intensity modulated radiation therapy. In Q. M. B. Soesanto, D. N. Bima, N. B. A. Prasetya, H. Sugito, & A. Maulidiyah (Eds.), 11th International Seminar on New Paradigm and Innovation on Natural Sciences and Its Application, ISNPINSA 2021: Developing Science and Technology Toward the New Normal Era Article 030022 (AIP Conference Proceedings; Vol. 2738). American Institute of Physics Inc.. https://doi.org/10.1063/5.0140137

Linggasari, Evi ; Hariyanto, Aditya P. ; Aisyah, St et al. / Evaluation of dosimetry in case of breast cancer post mastectomy with or without bolus based on silicone rubber using intensity modulated radiation therapy. 11th International Seminar on New Paradigm and Innovation on Natural Sciences and Its Application, ISNPINSA 2021: Developing Science and Technology Toward the New Normal Era. editor / Qidir Maulana Binu Soesanto ; Damar Nurwahyu Bima ; Nor Basid Adiwibawa Prasetya ; Heri Sugito ; Alik Maulidiyah. American Institute of Physics Inc., 2023. (AIP Conference Proceedings).

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title = "Evaluation of dosimetry in case of breast cancer post mastectomy with or without bolus based on silicone rubber using intensity modulated radiation therapy",

abstract = "Radiation therapy treatment for post-mastectomy breast cancer usually requires a bolus to raise the surface dose to a certain level. Bolus is a compensatory material that has properties such as soft tissue or water. Therefore, this study will evaluate the potential of using bolus and without bolus in post-mastectomy breast cancer cases. This study aims to analyze the percentage surface dose (PSD) on the solid water slab phantom, dose-volume histogram (DVH), profile dose, and surface dose in Postmastectomy Radiation Therapy (PMRT) cases with and without using a bolus made of silicone rubber with a thickness of 0.5 cm. The methods used in the present study involving measuring surface dose using bolus and without bolus on a solid water slab phantom with the TRS 398 protocol, making an Intensity-modulated radiation therapy (IMRT) planning system in 5 fields with angles of 30˚, 60˚, 230˚, 260˚and 320˚. Then analyzed DVH, dose profile, and surface dose using bolus and without bolus. Finally, verification of the plans that have been made is done using EBT3 film placed at 3 points (isocenter, right, and left). The results showed that DVH with bolus and without bolus met the recommendations of the International Commission on Radiation Unit (ICRU) 62, and organ at risk (OAR) still met the tolerance limit. The percentage of surface dose reached 80.02 \% and 29.75 \%, respectively, for with and without bolus. The surface dose in PMRT increased up to 35\%. Moreover, a bolus can increase the dose to the surface very well when the tumor cells are located on the surface compared to without a bolus.",

author = "Evi Linggasari and Hariyanto, \{Aditya P.\} and St Aisyah and Jannah, \{Nurul H.\} and Agus Rubiyanto and Mohammad Haekal and Muhamad Fadli and Endarko",

note = "Publisher Copyright: {\textcopyright} 2023 Author(s).; 11th International Seminar on New Paradigm and Innovation on Natural Sciences and Its Application: Developing Science and Technology Toward the New Normal Era, ISNPINSA 2021 ; Conference date: 14-10-2021 Through 15-10-2021",

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language = "English",

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publisher = "American Institute of Physics Inc.",

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booktitle = "11th International Seminar on New Paradigm and Innovation on Natural Sciences and Its Application, ISNPINSA 2021",

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Linggasari, E, Hariyanto, AP, Aisyah, S, Jannah, NH, Rubiyanto, A, Haekal, M, Fadli, M & Endarko 2023, Evaluation of dosimetry in case of breast cancer post mastectomy with or without bolus based on silicone rubber using intensity modulated radiation therapy. in QMB Soesanto, DN Bima, NBA Prasetya, H Sugito & A Maulidiyah (eds), 11th International Seminar on New Paradigm and Innovation on Natural Sciences and Its Application, ISNPINSA 2021: Developing Science and Technology Toward the New Normal Era., 030022, AIP Conference Proceedings, vol. 2738, American Institute of Physics Inc., 11th International Seminar on New Paradigm and Innovation on Natural Sciences and Its Application: Developing Science and Technology Toward the New Normal Era, ISNPINSA 2021, Semarang, Virtual, Indonesia, 14/10/21. https://doi.org/10.1063/5.0140137

Evaluation of dosimetry in case of breast cancer post mastectomy with or without bolus based on silicone rubber using intensity modulated radiation therapy. / Linggasari, Evi; Hariyanto, Aditya P.; Aisyah, St et al.
11th International Seminar on New Paradigm and Innovation on Natural Sciences and Its Application, ISNPINSA 2021: Developing Science and Technology Toward the New Normal Era. ed. / Qidir Maulana Binu Soesanto; Damar Nurwahyu Bima; Nor Basid Adiwibawa Prasetya; Heri Sugito; Alik Maulidiyah. American Institute of Physics Inc., 2023. 030022 (AIP Conference Proceedings; Vol. 2738).

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › peer-review

TY - GEN

T1 - Evaluation of dosimetry in case of breast cancer post mastectomy with or without bolus based on silicone rubber using intensity modulated radiation therapy

AU - Linggasari, Evi

AU - Hariyanto, Aditya P.

AU - Aisyah, St

AU - Jannah, Nurul H.

AU - Rubiyanto, Agus

AU - Haekal, Mohammad

AU - Fadli, Muhamad

AU - Endarko,

PY - 2023/6/2

Y1 - 2023/6/2

N2 - Radiation therapy treatment for post-mastectomy breast cancer usually requires a bolus to raise the surface dose to a certain level. Bolus is a compensatory material that has properties such as soft tissue or water. Therefore, this study will evaluate the potential of using bolus and without bolus in post-mastectomy breast cancer cases. This study aims to analyze the percentage surface dose (PSD) on the solid water slab phantom, dose-volume histogram (DVH), profile dose, and surface dose in Postmastectomy Radiation Therapy (PMRT) cases with and without using a bolus made of silicone rubber with a thickness of 0.5 cm. The methods used in the present study involving measuring surface dose using bolus and without bolus on a solid water slab phantom with the TRS 398 protocol, making an Intensity-modulated radiation therapy (IMRT) planning system in 5 fields with angles of 30˚, 60˚, 230˚, 260˚and 320˚. Then analyzed DVH, dose profile, and surface dose using bolus and without bolus. Finally, verification of the plans that have been made is done using EBT3 film placed at 3 points (isocenter, right, and left). The results showed that DVH with bolus and without bolus met the recommendations of the International Commission on Radiation Unit (ICRU) 62, and organ at risk (OAR) still met the tolerance limit. The percentage of surface dose reached 80.02 % and 29.75 %, respectively, for with and without bolus. The surface dose in PMRT increased up to 35%. Moreover, a bolus can increase the dose to the surface very well when the tumor cells are located on the surface compared to without a bolus.

AB - Radiation therapy treatment for post-mastectomy breast cancer usually requires a bolus to raise the surface dose to a certain level. Bolus is a compensatory material that has properties such as soft tissue or water. Therefore, this study will evaluate the potential of using bolus and without bolus in post-mastectomy breast cancer cases. This study aims to analyze the percentage surface dose (PSD) on the solid water slab phantom, dose-volume histogram (DVH), profile dose, and surface dose in Postmastectomy Radiation Therapy (PMRT) cases with and without using a bolus made of silicone rubber with a thickness of 0.5 cm. The methods used in the present study involving measuring surface dose using bolus and without bolus on a solid water slab phantom with the TRS 398 protocol, making an Intensity-modulated radiation therapy (IMRT) planning system in 5 fields with angles of 30˚, 60˚, 230˚, 260˚and 320˚. Then analyzed DVH, dose profile, and surface dose using bolus and without bolus. Finally, verification of the plans that have been made is done using EBT3 film placed at 3 points (isocenter, right, and left). The results showed that DVH with bolus and without bolus met the recommendations of the International Commission on Radiation Unit (ICRU) 62, and organ at risk (OAR) still met the tolerance limit. The percentage of surface dose reached 80.02 % and 29.75 %, respectively, for with and without bolus. The surface dose in PMRT increased up to 35%. Moreover, a bolus can increase the dose to the surface very well when the tumor cells are located on the surface compared to without a bolus.

UR - https://www.scopus.com/pages/publications/85163369217

U2 - 10.1063/5.0140137

DO - 10.1063/5.0140137

M3 - Conference contribution

AN - SCOPUS:85163369217

T3 - AIP Conference Proceedings

BT - 11th International Seminar on New Paradigm and Innovation on Natural Sciences and Its Application, ISNPINSA 2021

A2 - Soesanto, Qidir Maulana Binu

A2 - Bima, Damar Nurwahyu

A2 - Prasetya, Nor Basid Adiwibawa

A2 - Sugito, Heri

A2 - Maulidiyah, Alik

PB - American Institute of Physics Inc.

T2 - 11th International Seminar on New Paradigm and Innovation on Natural Sciences and Its Application: Developing Science and Technology Toward the New Normal Era, ISNPINSA 2021

Y2 - 14 October 2021 through 15 October 2021

ER -

Linggasari E, Hariyanto AP, Aisyah S, Jannah NH, Rubiyanto A, Haekal M et al. Evaluation of dosimetry in case of breast cancer post mastectomy with or without bolus based on silicone rubber using intensity modulated radiation therapy. In Soesanto QMB, Bima DN, Prasetya NBA, Sugito H, Maulidiyah A, editors, 11th International Seminar on New Paradigm and Innovation on Natural Sciences and Its Application, ISNPINSA 2021: Developing Science and Technology Toward the New Normal Era. American Institute of Physics Inc. 2023. 030022. (AIP Conference Proceedings). doi: 10.1063/5.0140137

Evaluation of dosimetry in case of breast cancer post mastectomy with or without bolus based on silicone rubber using intensity modulated radiation therapy

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