Extraction of Nigella sativa L. using supercritical CO2: A study of antioxidant activity of the extract

Siti Machmudah; Yuko Shiramizu; Motonobu Goto; Mitsuru Sasaki; Tsutomu Hirose

doi:10.1081/SS-200053005

Extraction of Nigella sativa L. using supercritical CO₂: A study of antioxidant activity of the extract

Siti Machmudah, Yuko Shiramizu, Motonobu Goto^*, Mitsuru Sasaki, Tsutomu Hirose

^*Corresponding author for this work

Kumamoto University

Research output: Contribution to journal › Article › peer-review

41 Citations (Scopus)

Abstract

Oil from Nigella sativa seed has been extracted by supercritical CO ₂ as a solvent at various pressures. In this study, two conditions of separation were used: they were low and high pressure separation. The antioxidant activity of the oil extracted was measured using an ultraviolet-visible spectrum (UV-Vis) spectrophotometer. There was no effect on the change of extraction pressure in apparatus with low pressure. The essential oil content in the extract from apparatus with high pressure was approximately two times higher than it was with low pressure. The antioxidant activity of Nigella sativa oil showed positive result. The antioxidant activity was obtained by the quantity of thymoquinone and carvacrol.

Original language	English
Pages (from-to)	1267-1275
Number of pages	9
Journal	Separation Science and Technology
Volume	40
Issue number	6
DOIs	https://doi.org/10.1081/SS-200053005
Publication status	Published - 2005
Externally published	Yes

Keywords

Antioxidant activity
Nigella sativa L
Supercritical CO extraction
Thymoquinone

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10.1081/SS-200053005

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abstract = "Oil from Nigella sativa seed has been extracted by supercritical CO 2 as a solvent at various pressures. In this study, two conditions of separation were used: they were low and high pressure separation. The antioxidant activity of the oil extracted was measured using an ultraviolet-visible spectrum (UV-Vis) spectrophotometer. There was no effect on the change of extraction pressure in apparatus with low pressure. The essential oil content in the extract from apparatus with high pressure was approximately two times higher than it was with low pressure. The antioxidant activity of Nigella sativa oil showed positive result. The antioxidant activity was obtained by the quantity of thymoquinone and carvacrol.",

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AU - Sasaki, Mitsuru

AU - Hirose, Tsutomu

PY - 2005

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AB - Oil from Nigella sativa seed has been extracted by supercritical CO 2 as a solvent at various pressures. In this study, two conditions of separation were used: they were low and high pressure separation. The antioxidant activity of the oil extracted was measured using an ultraviolet-visible spectrum (UV-Vis) spectrophotometer. There was no effect on the change of extraction pressure in apparatus with low pressure. The essential oil content in the extract from apparatus with high pressure was approximately two times higher than it was with low pressure. The antioxidant activity of Nigella sativa oil showed positive result. The antioxidant activity was obtained by the quantity of thymoquinone and carvacrol.

KW - Antioxidant activity

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Extraction of Nigella sativa L. using supercritical CO₂: A study of antioxidant activity of the extract

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Keywords

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