Fabrication and characterization of silica/Fe2.18Zn0.82O4 nanocomposites

Ahmad Taufiq; Anindya Bella Monica; Ainun Nikmah; Arif Hidayat; Sunaryono; Nurul Hidayat; Hendra Susanto; Erfan Handoko

doi:10.1063/5.0002465

Fabrication and characterization of silica/Fe_2.18Zn_0.82O₄ nanocomposites

Ahmad Taufiq^*, Anindya Bella Monica, Ainun Nikmah, Arif Hidayat, Sunaryono, Nurul Hidayat, Hendra Susanto, Erfan Handoko

^*Corresponding author for this work

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › peer-review

1 Citation (Scopus)

Abstract

In this paper, we report the fabrication and characterization of silica/Fe2.18Zn0.82O4 nanocomposites used as doxorubicin anti-cancer drug carrier. Silica/Fe2.18Zn0.82O4 nanocomposites were synthesized by using coprecipitation method followed by tetraethyl-orthosilicate hydrolysis process. The synthesis products were characterized by means of XRD, XRF, FTIR, UV Vis, and SEM. XRD characterization resulted in particle size of 7.14 nm. The presence of Si and Zn in the samples was confirmed from XRF characterization result: 49.2% for Si and 14.1% for Zn. Furthermore, functional groups of FTIR results also detected Si-O-Si bond in the wavelength of 1023 and 1091 cm^-1. Based on the analysis of drug loading, silica/Fe2.18Zn0.82O4 nanocomposites had exemplary absorbance for doxorubicin as an anti-cancer drug. The release profile of the drug also showed the possibility of its use in medical application since release kinetic indicated stable drug dose in a relatively long period.

Original language	English
Title of host publication	International Conference on Life Science and Technology, ICoLiST 2019
Editors	Ahmad Taufiq, Hendra Susanto, Hadi Nur, Muhammad Aziz, Chuang-Rung Chang, Hyohyemi Lee, Markus Diantoro, Nandang Mufti, Nik Ahmad Nizam Nik Malek, I. Ching Wang, Djoko Tjahnono Iskandar, Gereon Elbers, Sunaryono Sunaryono, Siti Zubaidah, Sumari Sumari, Aulanni'am, Asep Bayu Nandiyanto, Indra Wibowo, Adeodatus Yuda Handaya
Publisher	American Institute of Physics Inc.
ISBN (Electronic)	9780735419902
DOIs	https://doi.org/10.1063/5.0002465
Publication status	Published - 21 Apr 2020
Externally published	Yes
Event	2nd International Conference on Life Science and Technology, ICoLiST 2019 - Malang, East Java, Indonesia Duration: 12 Sept 2019 → 13 Sept 2019

Publication series

Name	AIP Conference Proceedings
Volume	2231
ISSN (Print)	0094-243X
ISSN (Electronic)	1551-7616

Conference

Conference	2nd International Conference on Life Science and Technology, ICoLiST 2019
Country/Territory	Indonesia
City	Malang, East Java
Period	12/09/19 → 13/09/19

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

Access to Document

10.1063/5.0002465

Cite this

Taufiq, A., Monica, A. B., Nikmah, A., Hidayat, A., Sunaryono, Hidayat, N., Susanto, H., & Handoko, E. (2020). Fabrication and characterization of silica/Fe_2.18Zn_0.82O₄ nanocomposites. In A. Taufiq, H. Susanto, H. Nur, M. Aziz, C.-R. Chang, H. Lee, M. Diantoro, N. Mufti, N. A. N. N. Malek, I. C. Wang, D. T. Iskandar, G. Elbers, S. Sunaryono, S. Zubaidah, S. Sumari, Aulanni'am, A. B. Nandiyanto, I. Wibowo, & A. Y. Handaya (Eds.), International Conference on Life Science and Technology, ICoLiST 2019 Article 2465 (AIP Conference Proceedings; Vol. 2231). American Institute of Physics Inc.. https://doi.org/10.1063/5.0002465

Taufiq, Ahmad ; Monica, Anindya Bella ; Nikmah, Ainun et al. / Fabrication and characterization of silica/Fe_2.18Zn_0.82O₄ nanocomposites. International Conference on Life Science and Technology, ICoLiST 2019. editor / Ahmad Taufiq ; Hendra Susanto ; Hadi Nur ; Muhammad Aziz ; Chuang-Rung Chang ; Hyohyemi Lee ; Markus Diantoro ; Nandang Mufti ; Nik Ahmad Nizam Nik Malek ; I. Ching Wang ; Djoko Tjahnono Iskandar ; Gereon Elbers ; Sunaryono Sunaryono ; Siti Zubaidah ; Sumari Sumari ; Aulanni'am ; Asep Bayu Nandiyanto ; Indra Wibowo ; Adeodatus Yuda Handaya. American Institute of Physics Inc., 2020. (AIP Conference Proceedings).

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title = "Fabrication and characterization of silica/Fe2.18Zn0.82O4 nanocomposites",

abstract = "In this paper, we report the fabrication and characterization of silica/Fe2.18Zn0.82O4 nanocomposites used as doxorubicin anti-cancer drug carrier. Silica/Fe2.18Zn0.82O4 nanocomposites were synthesized by using coprecipitation method followed by tetraethyl-orthosilicate hydrolysis process. The synthesis products were characterized by means of XRD, XRF, FTIR, UV Vis, and SEM. XRD characterization resulted in particle size of 7.14 nm. The presence of Si and Zn in the samples was confirmed from XRF characterization result: 49.2% for Si and 14.1% for Zn. Furthermore, functional groups of FTIR results also detected Si-O-Si bond in the wavelength of 1023 and 1091 cm-1. Based on the analysis of drug loading, silica/Fe2.18Zn0.82O4 nanocomposites had exemplary absorbance for doxorubicin as an anti-cancer drug. The release profile of the drug also showed the possibility of its use in medical application since release kinetic indicated stable drug dose in a relatively long period.",

author = "Ahmad Taufiq and Monica, {Anindya Bella} and Ainun Nikmah and Arif Hidayat and Sunaryono and Nurul Hidayat and Hendra Susanto and Erfan Handoko",

note = "Publisher Copyright: {\textcopyright} 2020 American Institute of Physics Inc.. All rights reserved.; 2nd International Conference on Life Science and Technology, ICoLiST 2019 ; Conference date: 12-09-2019 Through 13-09-2019",

year = "2020",

month = apr,

day = "21",

doi = "10.1063/5.0002465",

language = "English",

series = "AIP Conference Proceedings",

publisher = "American Institute of Physics Inc.",

editor = "Ahmad Taufiq and Hendra Susanto and Hadi Nur and Muhammad Aziz and Chuang-Rung Chang and Hyohyemi Lee and Markus Diantoro and Nandang Mufti and Malek, {Nik Ahmad Nizam Nik} and Wang, {I. Ching} and Iskandar, {Djoko Tjahnono} and Gereon Elbers and Sunaryono Sunaryono and Siti Zubaidah and Sumari Sumari and Aulanni'am and Nandiyanto, {Asep Bayu} and Indra Wibowo and Handaya, {Adeodatus Yuda}",

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Taufiq, A, Monica, AB, Nikmah, A, Hidayat, A, Sunaryono, , Hidayat, N, Susanto, H & Handoko, E 2020, Fabrication and characterization of silica/Fe_2.18Zn_0.82O₄ nanocomposites. in A Taufiq, H Susanto, H Nur, M Aziz, C-R Chang, H Lee, M Diantoro, N Mufti, NANN Malek, IC Wang, DT Iskandar, G Elbers, S Sunaryono, S Zubaidah, S Sumari, Aulanni'am, AB Nandiyanto, I Wibowo & AY Handaya (eds), International Conference on Life Science and Technology, ICoLiST 2019., 2465, AIP Conference Proceedings, vol. 2231, American Institute of Physics Inc., 2nd International Conference on Life Science and Technology, ICoLiST 2019, Malang, East Java, Indonesia, 12/09/19. https://doi.org/10.1063/5.0002465

Fabrication and characterization of silica/Fe_2.18Zn_0.82O₄ nanocomposites. / Taufiq, Ahmad; Monica, Anindya Bella; Nikmah, Ainun et al.
International Conference on Life Science and Technology, ICoLiST 2019. ed. / Ahmad Taufiq; Hendra Susanto; Hadi Nur; Muhammad Aziz; Chuang-Rung Chang; Hyohyemi Lee; Markus Diantoro; Nandang Mufti; Nik Ahmad Nizam Nik Malek; I. Ching Wang; Djoko Tjahnono Iskandar; Gereon Elbers; Sunaryono Sunaryono; Siti Zubaidah; Sumari Sumari; Aulanni'am; Asep Bayu Nandiyanto; Indra Wibowo; Adeodatus Yuda Handaya. American Institute of Physics Inc., 2020. 2465 (AIP Conference Proceedings; Vol. 2231).

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › peer-review

TY - GEN

T1 - Fabrication and characterization of silica/Fe2.18Zn0.82O4 nanocomposites

AU - Taufiq, Ahmad

AU - Monica, Anindya Bella

AU - Nikmah, Ainun

AU - Hidayat, Arif

AU - Sunaryono,

AU - Hidayat, Nurul

AU - Susanto, Hendra

AU - Handoko, Erfan

PY - 2020/4/21

Y1 - 2020/4/21

N2 - In this paper, we report the fabrication and characterization of silica/Fe2.18Zn0.82O4 nanocomposites used as doxorubicin anti-cancer drug carrier. Silica/Fe2.18Zn0.82O4 nanocomposites were synthesized by using coprecipitation method followed by tetraethyl-orthosilicate hydrolysis process. The synthesis products were characterized by means of XRD, XRF, FTIR, UV Vis, and SEM. XRD characterization resulted in particle size of 7.14 nm. The presence of Si and Zn in the samples was confirmed from XRF characterization result: 49.2% for Si and 14.1% for Zn. Furthermore, functional groups of FTIR results also detected Si-O-Si bond in the wavelength of 1023 and 1091 cm-1. Based on the analysis of drug loading, silica/Fe2.18Zn0.82O4 nanocomposites had exemplary absorbance for doxorubicin as an anti-cancer drug. The release profile of the drug also showed the possibility of its use in medical application since release kinetic indicated stable drug dose in a relatively long period.

AB - In this paper, we report the fabrication and characterization of silica/Fe2.18Zn0.82O4 nanocomposites used as doxorubicin anti-cancer drug carrier. Silica/Fe2.18Zn0.82O4 nanocomposites were synthesized by using coprecipitation method followed by tetraethyl-orthosilicate hydrolysis process. The synthesis products were characterized by means of XRD, XRF, FTIR, UV Vis, and SEM. XRD characterization resulted in particle size of 7.14 nm. The presence of Si and Zn in the samples was confirmed from XRF characterization result: 49.2% for Si and 14.1% for Zn. Furthermore, functional groups of FTIR results also detected Si-O-Si bond in the wavelength of 1023 and 1091 cm-1. Based on the analysis of drug loading, silica/Fe2.18Zn0.82O4 nanocomposites had exemplary absorbance for doxorubicin as an anti-cancer drug. The release profile of the drug also showed the possibility of its use in medical application since release kinetic indicated stable drug dose in a relatively long period.

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U2 - 10.1063/5.0002465

DO - 10.1063/5.0002465

M3 - Conference contribution

AN - SCOPUS:85092573112

T3 - AIP Conference Proceedings

BT - International Conference on Life Science and Technology, ICoLiST 2019

A2 - Taufiq, Ahmad

A2 - Susanto, Hendra

A2 - Nur, Hadi

A2 - Aziz, Muhammad

A2 - Chang, Chuang-Rung

A2 - Lee, Hyohyemi

A2 - Diantoro, Markus

A2 - Mufti, Nandang

A2 - Malek, Nik Ahmad Nizam Nik

A2 - Wang, I. Ching

A2 - Iskandar, Djoko Tjahnono

A2 - Elbers, Gereon

A2 - Sunaryono, Sunaryono

A2 - Zubaidah, Siti

A2 - Sumari, Sumari

A2 - Aulanni'am, null

A2 - Nandiyanto, Asep Bayu

A2 - Wibowo, Indra

A2 - Handaya, Adeodatus Yuda

PB - American Institute of Physics Inc.

T2 - 2nd International Conference on Life Science and Technology, ICoLiST 2019

Y2 - 12 September 2019 through 13 September 2019

ER -

Taufiq A, Monica AB, Nikmah A, Hidayat A, Sunaryono , Hidayat N et al. Fabrication and characterization of silica/Fe_2.18Zn_0.82O₄ nanocomposites. In Taufiq A, Susanto H, Nur H, Aziz M, Chang CR, Lee H, Diantoro M, Mufti N, Malek NANN, Wang IC, Iskandar DT, Elbers G, Sunaryono S, Zubaidah S, Sumari S, Aulanni'am, Nandiyanto AB, Wibowo I, Handaya AY, editors, International Conference on Life Science and Technology, ICoLiST 2019. American Institute of Physics Inc. 2020. 2465. (AIP Conference Proceedings). doi: 10.1063/5.0002465