Fast Microwave-Assisted Green Synthesis of Silver Nanoparticles Using Low Concentration of Seminyak (Champeria sp.) Leaf Extract

Muhammad Bagas Ananda, Fathan Aditya Sanjaya, Tami Bachrurozy, Helmi Majid Ar Rasyid, Anggraini Barlian, Akfiny Hasdi Aimon, Fitriyatul Qulub, Prihartini Widiyanti, Arie Wibowo*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

2 Citations (Scopus)

Abstract

Silver nanoparticles (AgNPs) are fascinating materials for biomedical applications thanks to their strong antibacterial activity and biocompatibility. This study applied the green synthesis method using 0.5 wt.% Seminyak leaf extract and assisted with one min microwave irradiation to enhance AgNPs formation. Extremely small sizes AgNPs with an average particle size of 9.1 ± 4.1 nm and spherical shapes were obtained. The synthesized AgNPs displayed potent antibacterial activity against Escherichia coli and Staphylococcus aureus bacteria with a zone of inhibition of 12.3 ± 0.1 and 13.7 ± 0.7 mm, respectively. The MTT assay results demonstrated that the cells’ viability of the obtained AgNPs was 88.5 ± 7.0 %, implying biocompatibility for biomedical applications.

Original languageEnglish
Pages (from-to)395-404
Number of pages10
JournalIndonesian Journal of Chemistry
Volume23
Issue number2
DOIs
Publication statusPublished - 2023

Keywords

  • Seminyak leaf extract
  • antibacterial materials
  • green synthesis
  • microwave irradiation
  • silver nanoparticles

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