Homogeneity index analysis in patients with lung cancer squamous cell carcinoma IIIB using SlicerRT

Radiation dose is the basis used to optimize lung cancer treatment, requiring the right and accurate amount. One of the steps used in optimizing treatment is radiotherapy treatment planning, which aims to maximize the dose targeted at tumor cells and minimize the dose to healthy organs. This study aims to evaluate the fulfillment of total dose standards for healthy organs and the homogeneity of dose distribution using the 3D slicer-Slicer RT software. The method used in this study used two CT data and RT-Structures of NSCLC-Radiomics with a diagnosis of stage IIIB squamous cell carcinoma from The Cancer Imaging Archive (TCIA), the exact location of cancer, and only one nodule. Network density values are calculated using segment statistics on 3D Slicer based on CT-DICOM information. Meanwhile, the treatment plan was built using 3D Slicer-SlicerRT with a 60 Gy/30 fraction dose. The treatment design uses four planes, and optimization combines the gantry angle and beams weight. The results showed that the treatment planning system using 3D Slicer-SlicerRT met the total dose standard for healthy organs and had a homogeneity index for the first and second patient was 0.004 and 0.009, respectively.