TY - JOUR
T1 - Liquid-Liquid Equilibria of Butyric Acid, Water, and Methyl Isobutyl Ketone with the Aid of Biological Buffer as a Green Auxiliary Agent
AU - Altway, Saidah
AU - Tiwikrama, Ardila Hayu
AU - Rahayu, Serli Dwi
AU - Zuchrillah, Daril Ridho
AU - Soeprijanto, Soeprijanto
AU - Ramli, Nadza Basyuni
AU - Maulidia, Melvin Iga
AU - Suprihatin, Suprihatin
N1 - Publisher Copyright:
© 2023 American Chemical Society.
PY - 2023/7/13
Y1 - 2023/7/13
N2 - Biological buffer has a significant impact on aqueous organic phase equilibria in extraction processes. This study investigated the effect of biological buffer on the efficacy of butyric acid extraction from aqueous solution utilizing methyl isobutyl ketone (MIBK) as the extraction solvent. The liquid-liquid equilibria (LLE) of quaternary systems of methyl isobutyl ketone (MIBK) + butyric acid + water + biological buffer MOPS [3-(N)-morpholino propane sulfonic acid], HEPES (2-(4-(2-hydroxyethyl)-1-piperazinyl)ethanesulfonic acid), or EPPS (4-(2-hydroxyethyl)-1-piperazine propanesulfonic acid) were determined at temperature T = 303.15 K (30 °C) and P = 0.1 MPa (atmospheric pressure). The addition of EPPS to the butyric acid aqueous solution resulted in superior extraction efficacy compared to the other biological buffers, as determined by experimental data. Generally, the extraction performance was in the order EPPS > MOPS > HEPES, which represented the buffering-out strength as well. The non-random two-liquid (NRTL) and UNIversal QUAsi Chemical (UNIQUAC) models fit well with the actual LLE data of the quaternary systems. The σ-profile analysis was also evaluated in this study. Additionally, a potential process flow sheet using biological buffer and MIBK solvent was suggested for removing butyric acid from its aqueous solution.
AB - Biological buffer has a significant impact on aqueous organic phase equilibria in extraction processes. This study investigated the effect of biological buffer on the efficacy of butyric acid extraction from aqueous solution utilizing methyl isobutyl ketone (MIBK) as the extraction solvent. The liquid-liquid equilibria (LLE) of quaternary systems of methyl isobutyl ketone (MIBK) + butyric acid + water + biological buffer MOPS [3-(N)-morpholino propane sulfonic acid], HEPES (2-(4-(2-hydroxyethyl)-1-piperazinyl)ethanesulfonic acid), or EPPS (4-(2-hydroxyethyl)-1-piperazine propanesulfonic acid) were determined at temperature T = 303.15 K (30 °C) and P = 0.1 MPa (atmospheric pressure). The addition of EPPS to the butyric acid aqueous solution resulted in superior extraction efficacy compared to the other biological buffers, as determined by experimental data. Generally, the extraction performance was in the order EPPS > MOPS > HEPES, which represented the buffering-out strength as well. The non-random two-liquid (NRTL) and UNIversal QUAsi Chemical (UNIQUAC) models fit well with the actual LLE data of the quaternary systems. The σ-profile analysis was also evaluated in this study. Additionally, a potential process flow sheet using biological buffer and MIBK solvent was suggested for removing butyric acid from its aqueous solution.
UR - http://www.scopus.com/inward/record.url?scp=85164450263&partnerID=8YFLogxK
U2 - 10.1021/acs.jced.3c00132
DO - 10.1021/acs.jced.3c00132
M3 - Article
AN - SCOPUS:85164450263
SN - 0021-9568
VL - 68
SP - 1706
EP - 1715
JO - Journal of Chemical and Engineering Data
JF - Journal of Chemical and Engineering Data
IS - 7
ER -