TY - JOUR
T1 - Magneto-Thermal Effect in Mn0.25Fe2.75O4-PEG Nanoparticles and Their Potential as Hyperthermia Therapy
AU - Sunaryono,
AU - Saputra, Kormil
AU - Hidayat, Arif
AU - Insjaf Yogihati, Chusnana
AU - Tri Wicaksono, Sigit
AU - Hidayat, Nurul
AU - Hidayat, Samsul
AU - Soontaranon, Siriwat
N1 - Publisher Copyright:
© Published under licence by IOP Publishing Ltd.
PY - 2019
Y1 - 2019
N2 - Mn0.25Fe2.75O4-PEG nanoparticles based on local iron sand were synthesized using the coprecipitation method. The characterization of sample was conducted using the X-ray Diffraction (XRD) instrument, Fourier Transform Infrared (FTIR), Small Angle X-Ray Scattering (SAXS), and Magneto-thermal each has a purpose to find out the formed phase structure, the adsorption pattern of sample functional group, nanoparticle distribution, and thermal effect of the sample. The results of characterization using XRD showing that the formed sample phase was in the form of the magnetite spinel structure. Through Rietica analysis and calculation using Debye-Scherrer, the sizes of nanoparticle samples were 7.9, 6.4, and 5.3 nm respectively with the addition of PEG concentration of 1000, 2000, and 4000. The adsorption of nanoparticle functional group was confirmed well with the appearance of Fe-O and Mn-O bound adsorption, at the wavenumbers of 430 cm-1 and 482 cm-1 respectively which were the representations of Mn0.25Fe2.75O4 material. Furthermore, the SAXS data analysis using the two lognormal method showed that the primary size of the particle sample was around 3 nm. Meanwhile, the secondary sizes of the sample were 8.5, 7.1, and 5.9 nm with the addition of PEG concentration of 1000, 2000, and 4000. Interestingly, Mn0.25Fe2.75O4-PEG nanoparticles of 1000, 2000, and 4000 characterized using the Magneto thermal instrument have the value of 1.079, 1.082, and 1.105 W/g respectively and was able to improve the temperature of 37 °C up to 38°C. These characteristics showed that the Mn0.25Fe2.75O4-PEG nanoparticles have potentials to become a unique material which can function as the material for hyperthermia therapy.
AB - Mn0.25Fe2.75O4-PEG nanoparticles based on local iron sand were synthesized using the coprecipitation method. The characterization of sample was conducted using the X-ray Diffraction (XRD) instrument, Fourier Transform Infrared (FTIR), Small Angle X-Ray Scattering (SAXS), and Magneto-thermal each has a purpose to find out the formed phase structure, the adsorption pattern of sample functional group, nanoparticle distribution, and thermal effect of the sample. The results of characterization using XRD showing that the formed sample phase was in the form of the magnetite spinel structure. Through Rietica analysis and calculation using Debye-Scherrer, the sizes of nanoparticle samples were 7.9, 6.4, and 5.3 nm respectively with the addition of PEG concentration of 1000, 2000, and 4000. The adsorption of nanoparticle functional group was confirmed well with the appearance of Fe-O and Mn-O bound adsorption, at the wavenumbers of 430 cm-1 and 482 cm-1 respectively which were the representations of Mn0.25Fe2.75O4 material. Furthermore, the SAXS data analysis using the two lognormal method showed that the primary size of the particle sample was around 3 nm. Meanwhile, the secondary sizes of the sample were 8.5, 7.1, and 5.9 nm with the addition of PEG concentration of 1000, 2000, and 4000. Interestingly, Mn0.25Fe2.75O4-PEG nanoparticles of 1000, 2000, and 4000 characterized using the Magneto thermal instrument have the value of 1.079, 1.082, and 1.105 W/g respectively and was able to improve the temperature of 37 °C up to 38°C. These characteristics showed that the Mn0.25Fe2.75O4-PEG nanoparticles have potentials to become a unique material which can function as the material for hyperthermia therapy.
UR - http://www.scopus.com/inward/record.url?scp=85065659473&partnerID=8YFLogxK
U2 - 10.1088/1757-899X/515/1/012008
DO - 10.1088/1757-899X/515/1/012008
M3 - Conference article
AN - SCOPUS:85065659473
SN - 1757-8981
VL - 515
JO - IOP Conference Series: Materials Science and Engineering
JF - IOP Conference Series: Materials Science and Engineering
IS - 1
M1 - 012008
T2 - International Conference on Condensed Matters and Advanced Materials 2018, IC2MAM 2018
Y2 - 5 September 2018
ER -