Mechanistic insights into laccase-mediated functionalisation of lignocellulose material

Gibson S. Nyanhongo, Tukayi Kudanga, Endry Nugroho Prasetyo, Georg M. Guebitz

Research output: Contribution to journalArticlepeer-review

30 Citations (Scopus)


Recent emerging studies on the grafting mechanisms of functional molecules onto complex lignocellulose moieties have shown useful insights and possibilities in opening new frontiers in the enzymatic development of multifunctional polymers. Thanks to these studies which have demonstrated in principle the ability of laccases to mediate the coupling of antimicrobial compounds, hydrophobic molecules, including application processes for the development of fibreboards, particle boards, laminates etc. Further, laccase mediated grafting strategies developed using small reactive molecules e.g. phenolic amines which impart reactive properties to an inert polymer demonstrates the remarkable opportunities of enzyme meditated functionalization of polymers. Therefore recent studies focusing on understanding the mechanistic basis of the coupling mechanisms in order to make meaningful contribution to the development of new processes and products are a welcome development.

Original languageEnglish
Pages (from-to)305-330
Number of pages26
JournalBiotechnology and Genetic Engineering Reviews
Issue number1
Publication statusPublished - 2010
Externally publishedYes


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