MULTIVARIATE ADAPTIVE BIVARIATE REGRESSION SPLINES (MABRS) BINARY RESPONSE FOR MODELING STROKE AND HYPERTENSION IN RSKD DADI CITY MAKASSAR

Research output: Contribution to journalArticlepeer-review

Abstract

Classification of health conditions with more than one correlated response variable is an important challenge in medical data analysis. This study proposes a Multivariate Adaptive Bivariate Regression Splines (MABRS) approach to classify stroke type (ischemic vs. hemorrhagic) and hypertension status simultaneously. Utilizing clinical data from stroke patients, the MABRS model was built based on the optimal parameter combination for each response. The results showed that the stroke type classification achieved a fairly good performance (accuracy 76.82%), with the most influential variables being obesity, hypercholesterolemia, and diabetes mellitus. In contrast, the hypertension classification model performed poorly (51.21% accuracy), although diabetes mellitus, gender, and age were identified as the main predictors. The MABRS approach has the advantage of capturing nonlinear relationships and interactions between predictor variables, while considering the correlation between two binary response variables in a unified model framework. These findings confirm the potential of MABRS in uncovering complex relationships between clinical variables and supporting data-driven medical decision-making, particularly in the management of comorbidities in stroke patients.

Original languageEnglish
Article number120
JournalCommunications in Mathematical Biology and Neuroscience
Volume2025
DOIs
Publication statusPublished - 2025

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

  1. SDG 3 - Good Health and Well-being
    SDG 3 Good Health and Well-being

Keywords

  • MABRS
  • binary response
  • hypertension
  • stroke

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