TY - JOUR
T1 - Novel Silicone Rubber and Polyvinyl Alcohol (PVA) Compound as Nucleus Pulposus Replacement in Intervertebral Disc Herniation Surgery
AU - Permana, Galih Indra
AU - Bajamal, Abdul Hafid
AU - Subagio, Eko Agus
AU - Parenrengi, Muhammad Arifin
AU - Rasyida, Amaliya
AU - Utomo, Budi
N1 - Publisher Copyright:
© 2022, Turkish Neurosurgery. All Rights Reserved.
PY - 2022
Y1 - 2022
N2 - AIM: to identify a novel material with biomechanical properties identical to the nucleus pulposus in the lumbar vertebrae of goats for use in intervertebral disc herniation surgery. material and methods: in this laboratory-based experimental study, the silicone rubber material test group consisted of sample compositions 35pva65sr, 30pva70sr, and 40pva60sr. axial compression mechanical tests were conducted to assess the biomechanical properties of the resulting material in terms of stress, strain, load, and displacement. results: the mechanical compression test results revealed that the stress (mpa) and strain (%) values of the 40pva60sr material were closest to the control group (p=1.00) with a load of 684 n in each group. the value of material displacement (mm) for 40pva60sr was also the closest to control (p=1.00) with a loading of 684 n. conclusion: the new material presents biomechanical properties closest to human nucleus pulposus and is promising in nucleus pulposus replacement therapy. further clinical research is needed to evaluate other biomechanical properties and the bioavailability of the novel material.
AB - AIM: to identify a novel material with biomechanical properties identical to the nucleus pulposus in the lumbar vertebrae of goats for use in intervertebral disc herniation surgery. material and methods: in this laboratory-based experimental study, the silicone rubber material test group consisted of sample compositions 35pva65sr, 30pva70sr, and 40pva60sr. axial compression mechanical tests were conducted to assess the biomechanical properties of the resulting material in terms of stress, strain, load, and displacement. results: the mechanical compression test results revealed that the stress (mpa) and strain (%) values of the 40pva60sr material were closest to the control group (p=1.00) with a load of 684 n in each group. the value of material displacement (mm) for 40pva60sr was also the closest to control (p=1.00) with a loading of 684 n. conclusion: the new material presents biomechanical properties closest to human nucleus pulposus and is promising in nucleus pulposus replacement therapy. further clinical research is needed to evaluate other biomechanical properties and the bioavailability of the novel material.
KW - Biomechanics
KW - Compression test
KW - Intervertebral disc herniation
KW - Polyvinyl alcohol (pva)
KW - Silicone rubber
UR - http://www.scopus.com/inward/record.url?scp=85138175560&partnerID=8YFLogxK
U2 - 10.5137/1019-5149.JTN.35925-21.3
DO - 10.5137/1019-5149.JTN.35925-21.3
M3 - Article
C2 - 35713254
AN - SCOPUS:85138175560
SN - 1019-5149
VL - 32
SP - 779
EP - 785
JO - Turkish Neurosurgery
JF - Turkish Neurosurgery
IS - 5
ER -