Porous silica nanomaterial derived from organic waste rice husk as highly potential drug delivery material

Rice became the main product of agriculture in agrarian countries including Indonesia. Rice husk were an organic-waste potentially as silica precursors. In other hand, silica extracted from rice husks in order to assess its possible use as a raw material to produce silica-based products. In this study, mesoporous silica nanoparticle (MSN) MCM-41 synthesized from rice husk with sol-gel method followed by hydrothermal. Acid leaching HCl followed by heat treatment at 600^oC in air ambient has been carried on rice husk to produce rice husk ash (RHA). The silica gel was prepared from sodium silicate by sodium hydroxide treatment and continued with acetic acid. Mesoporous silica had synthesized with CTAB as a surfactant-template. X-ray powder diffraction shown that mesoporous silica has an amorphous-like pattern. The FTIR spectrum of mesoporous silica MCM-41 has similar spectrum with Si-O-Si bond. MSN MCM-41 had a coral-like microstructure and had a hexagonal pore structure such as a honeycomb with a pore size of 2.535 nm. BET specific surface area is 825.365 m² /gr and average pore size is 6.104 nm.