TY - GEN
T1 - Preparation and performance evaluation of water-soluble chitosan-alginate capsules
AU - Fadlan, Arif
AU - Elanda, Febby Fedika
AU - Harmami, Harmami
AU - Ulfin, Ita
AU - Ni'Mah, Yatim Lailun
N1 - Publisher Copyright:
© 2020 Author(s).
PY - 2020/4/21
Y1 - 2020/4/21
N2 - Capsules were obtained from shrimp water-soluble chitosan (WSC) and alginate with 2:1, 3:1, 4:1, 5:1, 6:1 (w/w) ratios using 0.08% (w/v) of sodium dodecyl sulfate (SDS). The performance of the resulted capsules such as weight uniformity, degradation, swelling, drug release time, and solubility was evaluated. All capsules showed good weight uniformity according to the Indonesian Pharmacopoeia Standard. The higher ratio of WSC: alginate (6:1) produced capsules with the best properties in water and in 0.1 N HCl. The results achieved suggest that the capsules could be used for drug delivery systems.
AB - Capsules were obtained from shrimp water-soluble chitosan (WSC) and alginate with 2:1, 3:1, 4:1, 5:1, 6:1 (w/w) ratios using 0.08% (w/v) of sodium dodecyl sulfate (SDS). The performance of the resulted capsules such as weight uniformity, degradation, swelling, drug release time, and solubility was evaluated. All capsules showed good weight uniformity according to the Indonesian Pharmacopoeia Standard. The higher ratio of WSC: alginate (6:1) produced capsules with the best properties in water and in 0.1 N HCl. The results achieved suggest that the capsules could be used for drug delivery systems.
UR - http://www.scopus.com/inward/record.url?scp=85100987267&partnerID=8YFLogxK
U2 - 10.1063/5.0002687
DO - 10.1063/5.0002687
M3 - Conference contribution
AN - SCOPUS:85100987267
T3 - AIP Conference Proceedings
BT - 3rd International Seminar on Chemical Education
A2 - Fatimah, Is
A2 - Muhaimin, null
A2 - Musawwa, Muhammad Miqdam
PB - American Institute of Physics Inc.
T2 - 3rd International Seminar on Chemical Education: Trends, Applications, Changes in Chemical Education for the 4.0 Industrial Revolution, ISCE 2019
Y2 - 17 September 2019
ER -