TY - JOUR
T1 - Process development for the enrichment of curcuminoids in the extract of ionic type of NADES
AU - Rachmaniah, O.
AU - Muhsin, M. R.
AU - Widya, A. P.
AU - Rachimoellah, M.
N1 - Publisher Copyright:
© Published under licence by IOP Publishing Ltd.
PY - 2020/1/28
Y1 - 2020/1/28
N2 - Curcuminoids were successfully extracted from Curcuma zeodaria powder with Natural Deep Eutectic Solvents (NADES) as solvent. Ionic types of NADES such choline chloride-citric acid-water (CCCA-H2O = 1:1:18, mole ratio) and choline chloride-malic acid-water (CCMA-H2O = 1:1:18, mole ratio) gave the highest yield of extracted curcuminoids, ca. 0.2700.025 and 0.3550.055 mg/g respectively for CCCA and CCMA. However, the final product of the extracted curcuminoids was mixed in the NADES matrix. Hence, a separation process by means a solidification was mandatory. Isopropanol-n-hexane in both volume and molar ratio, i.e. 1:1, 1:1.5, 1:2, 2:1, and 2.5:1, were observed as a solvent in the solidification process as well as the solubility of curcuminoids in both isopropanol and n-hexane. Unfortunately, both of CCCA-H2O (1:1:18) or CCMA-H2O (1:1:18) and curcuminoids form a homogenous mixture with isopropanol. Therefore, all NADES constituents, i.e. choline chloride, citric acid/malic acid, and water, should be first removed before solidification process. Solubility of curcuminoids in isopropanol and n-hexane was, respectively, 3.2 mg/mL and 0.4 mg/mL at 40 °C. Isopropanol-hexane (1:1.5, v/v) give the highest recovery of curcuminoids, ca. 74.29%, by solidification process.
AB - Curcuminoids were successfully extracted from Curcuma zeodaria powder with Natural Deep Eutectic Solvents (NADES) as solvent. Ionic types of NADES such choline chloride-citric acid-water (CCCA-H2O = 1:1:18, mole ratio) and choline chloride-malic acid-water (CCMA-H2O = 1:1:18, mole ratio) gave the highest yield of extracted curcuminoids, ca. 0.2700.025 and 0.3550.055 mg/g respectively for CCCA and CCMA. However, the final product of the extracted curcuminoids was mixed in the NADES matrix. Hence, a separation process by means a solidification was mandatory. Isopropanol-n-hexane in both volume and molar ratio, i.e. 1:1, 1:1.5, 1:2, 2:1, and 2.5:1, were observed as a solvent in the solidification process as well as the solubility of curcuminoids in both isopropanol and n-hexane. Unfortunately, both of CCCA-H2O (1:1:18) or CCMA-H2O (1:1:18) and curcuminoids form a homogenous mixture with isopropanol. Therefore, all NADES constituents, i.e. choline chloride, citric acid/malic acid, and water, should be first removed before solidification process. Solubility of curcuminoids in isopropanol and n-hexane was, respectively, 3.2 mg/mL and 0.4 mg/mL at 40 °C. Isopropanol-hexane (1:1.5, v/v) give the highest recovery of curcuminoids, ca. 74.29%, by solidification process.
UR - http://www.scopus.com/inward/record.url?scp=85079736683&partnerID=8YFLogxK
U2 - 10.1088/1757-899X/732/1/012005
DO - 10.1088/1757-899X/732/1/012005
M3 - Conference article
AN - SCOPUS:85079736683
SN - 1757-8981
VL - 732
JO - IOP Conference Series: Materials Science and Engineering
JF - IOP Conference Series: Materials Science and Engineering
IS - 1
M1 - 012005
T2 - 1st Annual Technology, Applied Science, and Engineering Conference, ATASEC 2019
Y2 - 29 August 2019 through 30 August 2019
ER -