TY - GEN
T1 - Processing of polyphenolic composites with supercritical fluid anti-solvent technology
AU - Kurniawansyah, Firman
AU - Mammucari, Raffaella
AU - Foster, Neil R.
N1 - Publisher Copyright:
© 2017 Author(s).
PY - 2017/5/24
Y1 - 2017/5/24
N2 - Polyphenols have been developed, primarily exploiting their robust antioxidant properties, for medical and food applications. In spite of their advantages, polyphenolic compounds have drawbacks from their natural characteristics of being poorly soluble in aqueous solutions, thermo-labile and low oral bioavailaibility. In this article, strategy of processing with supercritical fluid (SCF) anti-solvent to improve the shortcomings is overviewed. Information obtained from the existing studies commonly confirms SCF technology applicability to produce composites of polyphenols with various morphology, size distributions and crystallinity. The application of SCF technology also enables to develop polyphenolic composites for alternative drug delivery such as in the pulmonary administrations.
AB - Polyphenols have been developed, primarily exploiting their robust antioxidant properties, for medical and food applications. In spite of their advantages, polyphenolic compounds have drawbacks from their natural characteristics of being poorly soluble in aqueous solutions, thermo-labile and low oral bioavailaibility. In this article, strategy of processing with supercritical fluid (SCF) anti-solvent to improve the shortcomings is overviewed. Information obtained from the existing studies commonly confirms SCF technology applicability to produce composites of polyphenols with various morphology, size distributions and crystallinity. The application of SCF technology also enables to develop polyphenolic composites for alternative drug delivery such as in the pulmonary administrations.
UR - http://www.scopus.com/inward/record.url?scp=85020468459&partnerID=8YFLogxK
U2 - 10.1063/1.4982312
DO - 10.1063/1.4982312
M3 - Conference contribution
AN - SCOPUS:85020468459
T3 - AIP Conference Proceedings
BT - International Seminar on Fundamental and Application of Chemical Engineering 2016, ISFAChE 2016
A2 - Widiyastuti, null
A2 - Taufany, Fadlilatul
A2 - Nurkhamidah, Siti
PB - American Institute of Physics Inc.
T2 - 3rd International Seminar on Fundamental and Application of Chemical Engineering 2016, ISFAChE 2016
Y2 - 1 November 2016 through 2 November 2016
ER -