Release kinetics performance of ibuprofen molecule from ordered mesoporous carbon with deferent concentration of drug loading

Maria Ulfa*, Rufaida M. Hasanah, Didik Prasetyoko

*Corresponding author for this work

Research output: Chapter in Book/Report/Conference proceedingConference contributionpeer-review

Abstract

In this study, we present a hard templating route for the synthesis of a high porosity and surface areas of ordered mesoporous carbon. Firstly, silica hard template prepared by self-assembly route using tetraethoxysilane (TEOS) and triblock copolymer Pluronic F127 which is employed as templating directing agents under acidic conditions. By using powder silica template and sucrose directly catalyzed by H2SO4 in the synthesis mixture, ordered mesoporous carbon were generated after calcination composite followed by organic removal in the common washing process. Character of the ordered mesoporous carbon was studied by nitrogen adsorption-desorption, scanning electron microscopy and surface analysis techniques. The drug delivery system performance was evaluated in a simulated body fluid after ibuprofen loading process. The present drug release route showed the advantage of being a slow rate of ibuprofen release so that ordered mesoporous carbon can be the new generation carrier material for ibuprofen molecule delivery system.

Original languageEnglish
Title of host publication2nd International Conference on Chemistry, Chemical Process and Engineering, IC3PE 2018
EditorsIs Fatimah, M. Arsyik Kurniawan S., Imam Sahroni, Laemthong Chuenchom, Miqdam Musawwa, Hideya Kawasaki, Azlan Kamari
PublisherAmerican Institute of Physics Inc.
ISBN (Electronic)9780735417465
DOIs
Publication statusPublished - 29 Oct 2018
Event2nd International Conference on Chemistry, Chemical Process and Engineering 2018, IC3PE 2018 - Yogyakarta, Indonesia
Duration: 14 Aug 2018 → …

Publication series

NameAIP Conference Proceedings
Volume2026
ISSN (Print)0094-243X
ISSN (Electronic)1551-7616

Conference

Conference2nd International Conference on Chemistry, Chemical Process and Engineering 2018, IC3PE 2018
Country/TerritoryIndonesia
CityYogyakarta
Period14/08/18 → …

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