TY - GEN
T1 - Selective Histamine Detection using Fluorescent Organic Nanocrystal-Immobilized-Microfluidic Paper Analytical Device
AU - Grasianto,
AU - Fukuyama, Mao
AU - Kasuya, Motohiro
AU - Mott, Derrick
AU - Baptista, Carlos
AU - Koseki, Yoshitaka
AU - Kasai, Hitoshi
AU - Akutagawa, Tomoyuki
AU - Hibara, Akihide
N1 - Publisher Copyright:
© 2021 MicroTAS 2021 - 25th International Conference on Miniaturized Systems for Chemistry and Life Sciences. All rights reserved.
PY - 2021
Y1 - 2021
N2 - Monitoring toxic biogenic amines is one of the critical aspects of food quality. Microfluidic paper analytical devices (µPADs) are promising for monitoring biogenic amines because they offer low cost, analyze in a short time, and require a simple operation. In this work, we demonstrated the utilization of fluorescent organic nanocrystal (NCs), 3-(2-benzothiazolyl)-4-hydroxy-benzenesulfonic acid (BHB), immobilized on µPADs for histamine detection. By controlling the pH using phosphate buffer pH 7.6, BHB NCs showed good selectivity to histamine over other biogenic amines. By applying a proper volume of aqueous sample solution, BHB NCs show an obvious color change even at a low ppm level which is possible to detect the histamine in a real sample application.
AB - Monitoring toxic biogenic amines is one of the critical aspects of food quality. Microfluidic paper analytical devices (µPADs) are promising for monitoring biogenic amines because they offer low cost, analyze in a short time, and require a simple operation. In this work, we demonstrated the utilization of fluorescent organic nanocrystal (NCs), 3-(2-benzothiazolyl)-4-hydroxy-benzenesulfonic acid (BHB), immobilized on µPADs for histamine detection. By controlling the pH using phosphate buffer pH 7.6, BHB NCs showed good selectivity to histamine over other biogenic amines. By applying a proper volume of aqueous sample solution, BHB NCs show an obvious color change even at a low ppm level which is possible to detect the histamine in a real sample application.
KW - Biogenic Amines
KW - Enrichment
KW - Fluorescent Organic Nanocrystal
KW - Histamine
UR - https://www.scopus.com/pages/publications/85136927884
M3 - Conference contribution
AN - SCOPUS:85136927884
T3 - MicroTAS 2021 - 25th International Conference on Miniaturized Systems for Chemistry and Life Sciences
SP - 1569
EP - 1570
BT - MicroTAS 2021 - 25th International Conference on Miniaturized Systems for Chemistry and Life Sciences
PB - Chemical and Biological Microsystems Society
T2 - 25th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2021
Y2 - 10 October 2021 through 14 October 2021
ER -