Simulation of single particle flowing in a microfluidic device using molecular dynamics method

Sparisoma Viridi, Freddy Haryanto, Isa Anshori, Mohammad Haekal

Research output: Contribution to journalConference articlepeer-review


Blood cells are modeled as spherical particles that flow through a microfluidic device with one inlet and two outlet channels, which is designed as a separator of blood particles. Molecular dynamics (MD) method was used intuitively in the simulation with the help of Semi-Circle Segmented Path Generator (SCSPG) as an approximation in creating fluid profile along the device channel. The trajectories generated from SCSPG was advanced using a fully developed Poiseuille flow with maximum fluid speed on the trajectories and the tails of speed distribution which was extended to the size of the channel with speed of zero at the channel walls. It has been observed that for a single particle trajectory the outlet channel was chosen by the particle depends on the axial position of the particles. Mass of particle determines how hard the particle deflects due to fluid profile. A better design is proposed in this work for separating two groups of particles with different size.

Original languageEnglish
Article number012062
JournalJournal of Physics: Conference Series
Issue number1
Publication statusPublished - 15 Jun 2020
Event3rd Annual Scientific Meeting on Medical Physics and Biophysics, PIT-FMB in conjunction with the 17th South-East Asia Congress of Medical Physics, SEACOMP 2019 - Bali, Indonesia
Duration: 8 Aug 201910 Aug 2019


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