TY - JOUR
T1 - Study of Nano-Hydroxyapatite:Poly Lactide Acid (n-HA:PLA) Composites and Their Biocompatibility, Bioactivity, and Biodegradability Characteristics
AU - Yudyanto,
AU - Hardianti, D.
AU - Hartatiek,
AU - Hidayat, N.
AU - Kurniawan, R.
N1 - Publisher Copyright:
© Published under licence by IOP Publishing Ltd.
PY - 2019
Y1 - 2019
N2 - A synthesis of nano-hydroxyapatite:polylactide acid (n-HA:PLA) composites based on natural materials has been performed. The synthesis was performed using sonication method, with a variation of n-HA:PLA ratio of 90:10, 80:20, 70:30, 60:40, 50:50 in %wt. The crystal structure and morphology of the sample were characterized by using X-ray diffractometer (XRD) and scanning electron microscopy (SEM). The bioactivity and biodegradable tests were performed in vitro using Krebs solution. Meanwhile, the biocompatibility test was performed by a separate bath organ method. The results show that for all compositions of n-HA:PLA exhibit a biocompatible characteristic. The sample with a ratio of 90:10 %wt shows higher bioactivity and biodegradability properties than other compositions. Our result would give a good understanding of the synthesis and biocompatibility, bioactivity, and biodegradability of n-HA:PLA composite, which is crucial for bone regeneration.
AB - A synthesis of nano-hydroxyapatite:polylactide acid (n-HA:PLA) composites based on natural materials has been performed. The synthesis was performed using sonication method, with a variation of n-HA:PLA ratio of 90:10, 80:20, 70:30, 60:40, 50:50 in %wt. The crystal structure and morphology of the sample were characterized by using X-ray diffractometer (XRD) and scanning electron microscopy (SEM). The bioactivity and biodegradable tests were performed in vitro using Krebs solution. Meanwhile, the biocompatibility test was performed by a separate bath organ method. The results show that for all compositions of n-HA:PLA exhibit a biocompatible characteristic. The sample with a ratio of 90:10 %wt shows higher bioactivity and biodegradability properties than other compositions. Our result would give a good understanding of the synthesis and biocompatibility, bioactivity, and biodegradability of n-HA:PLA composite, which is crucial for bone regeneration.
UR - http://www.scopus.com/inward/record.url?scp=85065645363&partnerID=8YFLogxK
U2 - 10.1088/1757-899X/515/1/012034
DO - 10.1088/1757-899X/515/1/012034
M3 - Conference article
AN - SCOPUS:85065645363
SN - 1757-8981
VL - 515
JO - IOP Conference Series: Materials Science and Engineering
JF - IOP Conference Series: Materials Science and Engineering
IS - 1
M1 - 012034
T2 - International Conference on Condensed Matters and Advanced Materials 2018, IC2MAM 2018
Y2 - 5 September 2018
ER -