Supercritical Carbon Dioxide Extraction of Citronella Oil Review: Process Optimization, Product Quality, and Applications

Nicky Rahmana Putra, Ahmad Hazim Abdul Aziz*, Dwila Nur Rizkiyah, Mohd Azizi Che Yunus, Ratna Surya Alwi, Reny Tri Anggraini, Siti Khodijah, Irianto Irianto, Lailatul Qomariyah

*Corresponding author for this work

Research output: Contribution to journalReview articlepeer-review


This review paper explores the utilization of supercritical carbon dioxide (SC-CO2) extraction to isolate citronella oil, delving into its multifaceted dimensions, including process optimization, product quality enhancement, and diverse potential applications. Citronella oil, renowned for its myriad bioactive compounds with demonstrated health benefits, is a coveted essential oil in the pharmaceutical, cosmetics, and food industries. The transition from traditional extraction techniques to SC-CO2 extraction presents a paradigm shift due to its manifold advantages, such as heightened yield rates, expedited extraction durations, and elevated product quality. However, the efficacy of SC-CO2 extraction is intricately interwoven with an array of parameters encompassing pressure, temperature, flow rate, particle size, and co-solvent ratios. Accordingly, meticulous process optimization is indispensable in achieving the desired product quality while maximizing yield. Furthermore, the paper explores the extensive spectrum of potential applications for citronella oil, extending its reach into formulations with antimicrobial, insecticidal, and antioxidant properties. These applications underscore the versatility and commercial appeal of citronella oil. The review establishes SC-CO2 extraction of citronella oil as a promising and sustainable alternative to conventional extraction methodologies, offering myriad applications across the pharmaceutical, cosmetics, and food sectors. This scholarly work provides valuable insights into the intricacies of process optimization and product quality. It outlines future perspectives and avenues for further exploration in SC-CO2 extraction of citronella oil.

Original languageEnglish
Pages (from-to)1043-1069
Number of pages27
JournalPertanika Journal of Science and Technology
Issue number3
Publication statusPublished - 1 Apr 2024


  • Citronella
  • optimization
  • product quality
  • supercritical carbon dioxide

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