Abstract

The synthesis and anticancer study of 5,7-dibromoisatin-derived hydrazine carbothioamide and its nickel(II) complex are reported in this study. The ligand was successfully synthesized from 4-phenyl-3-thiosemicarbazide and 5,7- dibromoisatin. The ligand and its complex were characterized by spectroscopic methods (UV, IR, NMR, MS) and thermogravimetric analysis. The complex has shown LC50 result of 270 ug/mL in anticancer test using HeLa cells.

Original languageEnglish
Title of host publication14th Joint Conference on Chemistry 2019
EditorsFitria Rahmawati, Teguh Endah Saraswati, Khoirina Dwi Nugrahaningtyas, Soerya Dewi Marliyana, Triana Kusumaningsih
PublisherAmerican Institute of Physics Inc.
ISBN (Electronic)9780735419964
DOIs
Publication statusPublished - 2 Jun 2020
Event14th Joint Conference on Chemistry 2019, JCC 2019 - Surakarta, Indonesia
Duration: 10 Sept 201911 Sept 2019

Publication series

NameAIP Conference Proceedings
Volume2237
ISSN (Print)0094-243X
ISSN (Electronic)1551-7616

Conference

Conference14th Joint Conference on Chemistry 2019, JCC 2019
Country/TerritoryIndonesia
CitySurakarta
Period10/09/1911/09/19

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