TY - JOUR
T1 - Synthesis of alternative hard capsule from carrageenan and starch using glycerol as plasticizer
AU - Mahardika, Gading Bagus
AU - Salsabila, Ranandhiya
AU - Kurniawansyah, Firman
AU - Ni'Mah, Hikmatun
AU - Nurtono, Tantular
AU - Mahfud, Mahfud
N1 - Publisher Copyright:
© 2023 Author(s).
PY - 2023/8/21
Y1 - 2023/8/21
N2 - Capsule is a material used to facilitate drugs for an improved protection and enhanced consumers compliance. Due to several reasons such as related with consumers believe and other personal preferences, alternative materials for capsule manufacturing have been investigated. This research uses carrageenan from seaweed utilizing Indonesia marine resources. The objective of this research is to investigate potency of carrageenan to substitute gelatin as alternative material of hard capsule. Carrageenan was mixed with starch of cassava, using glycerol as plasticizer in various compositions at 70-80?C. As much as 2?g of sodium tri-polyphosphate (STPP) was added as crosslinker agent. The suspensions were molded by using stainless steel dipping pen. Sample analysis showed produced hard capsule was in the range weight of 87 to 105?mg, and dissolution time of minute, which informs potential of this study for further developments.
AB - Capsule is a material used to facilitate drugs for an improved protection and enhanced consumers compliance. Due to several reasons such as related with consumers believe and other personal preferences, alternative materials for capsule manufacturing have been investigated. This research uses carrageenan from seaweed utilizing Indonesia marine resources. The objective of this research is to investigate potency of carrageenan to substitute gelatin as alternative material of hard capsule. Carrageenan was mixed with starch of cassava, using glycerol as plasticizer in various compositions at 70-80?C. As much as 2?g of sodium tri-polyphosphate (STPP) was added as crosslinker agent. The suspensions were molded by using stainless steel dipping pen. Sample analysis showed produced hard capsule was in the range weight of 87 to 105?mg, and dissolution time of minute, which informs potential of this study for further developments.
UR - http://www.scopus.com/inward/record.url?scp=85176963544&partnerID=8YFLogxK
U2 - 10.1063/5.0132160
DO - 10.1063/5.0132160
M3 - Conference article
AN - SCOPUS:85176963544
SN - 0094-243X
VL - 2818
JO - AIP Conference Proceedings
JF - AIP Conference Proceedings
IS - 1
M1 - 090001
T2 - 3rd International Conference on Chemistry and Material Science, IC2MS 2021
Y2 - 12 October 2021 through 13 October 2021
ER -
