Tailoring properties of acidic types of Natural Deep Eutectics Solvents (NADES): Enhanced solubility of curcuminoids from curcuma zeodaria

Orchidea Rachmaniah*, Lailatul Jumiati Fazriyah, Nurul Hesti Seftiyani, M. Rachimoellah

*Corresponding author for this work

Research output: Contribution to journalConference articlepeer-review

10 Citations (Scopus)

Abstract

Recently Natural Deep Eutectic Solvents (NADES) show their potential as a promising green solvents at 21th century for extraction of natural products. Rutin, a poorly water soluble flavonoid, was reported better solubilized in NADES than in water as well as a paclitaxel and ginkgolide B, a completely water-insoluble compound. In case of curcuminoids, phenolic compounds from powder of Curcuma Zeodaria shown better solubilized in acidic type of NADES such malic acid-sucrose-water (MAS-H2O = 1:1:11, mole ratio) and citric acid-sucrose-water (CAS-H2O = 1:2:15, mole ratio) compare to water and ethanol. Indicating that NADES, a water-based solvent, appropriate for extracting curcuminoids. However, the inherent high viscosity of NADES hamper the process extraction. Lowering the viscosity, water content of NADES is varied, adding a certain amount of water up to 60% of water content. All the varied water content of both CAS-H2O and MAS-H2O were successfully extracted curcuminoids. Yielded 0.06-0.16 mg curcuminoids/g dry weight. However, 60% of water content of both CAS-H2O and MAS-H2O gave more or less similar value of curcuminoids to CAS-H2O (20% of water) and MAS-H2O (30% of water). Curcuminoids is more stable in CAS-H2O compare to MAS-H2O for 96 h of time duration.

Original languageEnglish
Article number01011
JournalMATEC Web of Conferences
Volume156
DOIs
Publication statusPublished - 14 Mar 2018
Event24th Regional Symposium on Chemical Engineering, RSCE 2017 - Semarang, Indonesia
Duration: 15 Nov 201716 Nov 2017

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