Public health centre is one of the health services under the auspices of the UPTD Health Office, which is responsible for local community health services. Public health centre must manage the stock of medicines as well as possible to meet the needs of the community. The problem that occurs in the public health centre is overstock. There is a big gap between the supply and the need for medicines by the community. This can lead to high total inventory costs. Based on these problems, it is necessary to classify and plan medicines supply policies. In this study, as many as 143 types of medicines were classified using the ABC-Fuzzy Classification. This classification process produces three categories, namely very important, important, and unimportant. Furthermore, the calculation process will be carried out using the probabilistic periodic review method to determine inventory policy planning. The classification process for medicines using ABC-Fuzzy Classification analysis resulted in 21 medicines into the very important category, 33 medicines into the important category, and 89 medicines into the unimportant category. Then the results of calculations using a probabilistic periodic review resulted in a total proposed cost of Rp649,569,938, or a saving of 20.13%.