TY - GEN
T1 - The relationship of secondary metabolites
T2 - 3rd International Seminar on Chemistry: Green Chemistry and Its Role for Sustainability, ISOC 2018
AU - Fitriana, Wiwit Denny
AU - Istiqomah, Sri Banun Titi
AU - Ersam, Taslim
AU - Fatmawati, Sri
N1 - Publisher Copyright:
© 2018 Author(s).
PY - 2018/12/14
Y1 - 2018/12/14
N2 - Indonesian traditional herbal medicine for post partum contains many plants such as Kunyit (Curcuma longa), meniran (Phyllanthus urinaria), akar manis (Glycyrrhiza glabra), lempuyang (Zingiber zerumbet), temulawak (Curcuma zanthorrhiza), jungrahap (Baeckea frutescens L.), bangle (Zingiber montanum), binahong (Anredera cordifolia), asem (Tamarindus Indica). These plants are important sources of phenolic compounds such as flavonoid, quercetin, kaempherol that potentially act as antioxidant. Antioxidants are important subtances which possess the ability to protect the body from damage caused by free radical oxidative stress. The post partum herbal medicine were extracted using aquades. The antioxidant activity of extracts was evaluated using 1,1-diphenyl-2-picrylhydrazyl (DPPH) free radical scavenging activity assay and an improved (2,2'-azino-bis-[3-ethylbenzothiazoline sulphonate]) ABTS radical cation decolorization assay using in vitro. Trolox was used as the standard with IC50 5.89 μg/mL in DPPH assay and 3.06 μg/mL in ABTS assay. The variant B1 showed the highest free radical scavenging activity (IC50=28.37 μg/mL in DPPH assay and IC50=27.17 μg/mL in ABTS assay). The variant E2 also showed the highest free radical scavenging activity (IC50=29.56 μg/mL in DPPH assay and IC50=26.16 μg/mL in ABTS assay). This study indicated that Indonesian traditional herbal medicine possess antioxidant activity and it needs to be investigated more for other bioactivity such as antimicrobial and anticholestrol.
AB - Indonesian traditional herbal medicine for post partum contains many plants such as Kunyit (Curcuma longa), meniran (Phyllanthus urinaria), akar manis (Glycyrrhiza glabra), lempuyang (Zingiber zerumbet), temulawak (Curcuma zanthorrhiza), jungrahap (Baeckea frutescens L.), bangle (Zingiber montanum), binahong (Anredera cordifolia), asem (Tamarindus Indica). These plants are important sources of phenolic compounds such as flavonoid, quercetin, kaempherol that potentially act as antioxidant. Antioxidants are important subtances which possess the ability to protect the body from damage caused by free radical oxidative stress. The post partum herbal medicine were extracted using aquades. The antioxidant activity of extracts was evaluated using 1,1-diphenyl-2-picrylhydrazyl (DPPH) free radical scavenging activity assay and an improved (2,2'-azino-bis-[3-ethylbenzothiazoline sulphonate]) ABTS radical cation decolorization assay using in vitro. Trolox was used as the standard with IC50 5.89 μg/mL in DPPH assay and 3.06 μg/mL in ABTS assay. The variant B1 showed the highest free radical scavenging activity (IC50=28.37 μg/mL in DPPH assay and IC50=27.17 μg/mL in ABTS assay). The variant E2 also showed the highest free radical scavenging activity (IC50=29.56 μg/mL in DPPH assay and IC50=26.16 μg/mL in ABTS assay). This study indicated that Indonesian traditional herbal medicine possess antioxidant activity and it needs to be investigated more for other bioactivity such as antimicrobial and anticholestrol.
KW - ABTS
KW - DPPH
KW - Indonesian traditional herbal medicine
KW - phenolic compounds
KW - post partum herbal medicine
UR - http://www.scopus.com/inward/record.url?scp=85059013221&partnerID=8YFLogxK
U2 - 10.1063/1.5082501
DO - 10.1063/1.5082501
M3 - Conference contribution
AN - SCOPUS:85059013221
T3 - AIP Conference Proceedings
BT - 3rd International Seminar on Chemistry
A2 - Kurniawan, Fredy
A2 - Kusumawati, Yuly
A2 - Fatmawati, Sri
A2 - Juwono, Hendro
A2 - Purnomo, Adi Setyo
PB - American Institute of Physics Inc.
Y2 - 18 July 2018 through 19 July 2018
ER -