Turmerones compounds extract as potential photosensitizer achievement for blood cancer

Putri Wulandari; Ulya Farahdina; Nasori Nasori

doi:10.1063/5.0228100

Turmerones compounds extract as potential photosensitizer achievement for blood cancer

Putri Wulandari, Ulya Farahdina, Nasori Nasori^*

^*Corresponding author for this work

Research output: Contribution to journal › Conference article › peer-review

Abstract

Blood cancer is an abnormal growth in white blood cells that causes the body to be too weak to fight infection. Blood cancer is included in liquid cancer, so it quickly spreads to other organs of the body. An alternative treatment for leukemia can be done with photodynamic therapy (PDT). PDT shows significantly lower toxic side effects because photosensitizer (PS) accumulates in significantly higher concentrations in cancer cells than in normal cells. The PS used in this study is made from natural ingredients, namely turmeric through an extraction process by maceration method. Through the manufacture of PS through turmeric extraction produces a turmerone with a maximum absorbance wavelength of 400-500 nm. These results provide a potential PS for blood cancer treatment using PDT from the natural ingredient turmeric.

Original language	English
Article number	020001
Journal	AIP Conference Proceedings
Volume	3210
Issue number	1
DOIs	https://doi.org/10.1063/5.0228100
Publication status	Published - 28 Aug 2024
Event	21st South-East Asian Congress of Medical Physics, SEACOMP 2023, held in conjunction with the 6th Annual Scientific Meeting on Medical Physics and Biophysics, PIT-FMB 2023 - Mataram, Indonesia Duration: 10 Aug 2023 → 13 Aug 2023

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10.1063/5.0228100

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title = "Turmerones compounds extract as potential photosensitizer achievement for blood cancer",

abstract = "Blood cancer is an abnormal growth in white blood cells that causes the body to be too weak to fight infection. Blood cancer is included in liquid cancer, so it quickly spreads to other organs of the body. An alternative treatment for leukemia can be done with photodynamic therapy (PDT). PDT shows significantly lower toxic side effects because photosensitizer (PS) accumulates in significantly higher concentrations in cancer cells than in normal cells. The PS used in this study is made from natural ingredients, namely turmeric through an extraction process by maceration method. Through the manufacture of PS through turmeric extraction produces a turmerone with a maximum absorbance wavelength of 400-500 nm. These results provide a potential PS for blood cancer treatment using PDT from the natural ingredient turmeric.",

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T1 - Turmerones compounds extract as potential photosensitizer achievement for blood cancer

AU - Wulandari, Putri

AU - Farahdina, Ulya

AU - Nasori, Nasori

PY - 2024/8/28

Y1 - 2024/8/28

N2 - Blood cancer is an abnormal growth in white blood cells that causes the body to be too weak to fight infection. Blood cancer is included in liquid cancer, so it quickly spreads to other organs of the body. An alternative treatment for leukemia can be done with photodynamic therapy (PDT). PDT shows significantly lower toxic side effects because photosensitizer (PS) accumulates in significantly higher concentrations in cancer cells than in normal cells. The PS used in this study is made from natural ingredients, namely turmeric through an extraction process by maceration method. Through the manufacture of PS through turmeric extraction produces a turmerone with a maximum absorbance wavelength of 400-500 nm. These results provide a potential PS for blood cancer treatment using PDT from the natural ingredient turmeric.

AB - Blood cancer is an abnormal growth in white blood cells that causes the body to be too weak to fight infection. Blood cancer is included in liquid cancer, so it quickly spreads to other organs of the body. An alternative treatment for leukemia can be done with photodynamic therapy (PDT). PDT shows significantly lower toxic side effects because photosensitizer (PS) accumulates in significantly higher concentrations in cancer cells than in normal cells. The PS used in this study is made from natural ingredients, namely turmeric through an extraction process by maceration method. Through the manufacture of PS through turmeric extraction produces a turmerone with a maximum absorbance wavelength of 400-500 nm. These results provide a potential PS for blood cancer treatment using PDT from the natural ingredient turmeric.

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DO - 10.1063/5.0228100

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VL - 3210

JO - AIP Conference Proceedings

JF - AIP Conference Proceedings

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T2 - 21st South-East Asian Congress of Medical Physics, SEACOMP 2023, held in conjunction with the 6th Annual Scientific Meeting on Medical Physics and Biophysics, PIT-FMB 2023

Y2 - 10 August 2023 through 13 August 2023

ER -

Turmerones compounds extract as potential photosensitizer achievement for blood cancer

Abstract

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